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Molecule Parameter List for aTRKb | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| aTRKb participated as | Molecule | Sum total of | Input | Product | Ligand/Activator | Modifier |
| No. of occurrences | 1 | 0 | 0 | 1 | 1 | 0 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| syn_CaMKIII | 114 | Pathway | BDNF_g, S6K_g, CaMKIII_g |
| This model was used to generate Fig 3 supp A to F in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621. | |||
aTRKb acting as a Molecule in syn_CaMKIII Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) |
| aTRKb | syn_CaMKIII Accession No. : 114 | BDNF_g Pathway No. : 1157 | 0 |
aTRKb acting as prd in syn_CaMKIII Network
| Accession Name | Pathway Name | Product | Input | Ligand | Inhibit | KA | tau | Modifier | Addition_parameter | ||
| syn_CaMKIII Accession No: 114 | BDNF_g Pathway No:1157 | aTRKb | TRKb | BDNF | 0 | 0.0001 (uM) | 70 (s) | aS6K aS6K Amod : 0Nmod : 2 Kmod : 0.53 |
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aTRKb acting as ligant in syn_CaMKIII Network
| Accession Name | Pathway Name | Product | Input | Ligand | Inhibit | KA | tau | Modifier | Addition_parameter | ||
| syn_CaMKIII Accession No: 114 | S6K_g Pathway No:1158 | aS6K | S6K | 2 * aTRKb | 0 | 0.92 (uM) | 507 (s) | Ca Ca Ca Ca Amod : 113Nmod : 4 Kmod : 0.434 |
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