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Molecule Parameter List for L-Arg

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
L-Arg participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000010

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
Stuehr_NOS12Pathway
NOS 
This is a model of neuronal Nitric Oxide Synthase expressed in Escherichia coli based on Santolini J. et al. J Biol Chem. (2001) 276(2):1233-43. The rates have been converted by 2x for every 10 degrees C. The original temperature was 10 degree C, cell temperature is assumed 30 degree C, so the conversion factor is 4.

L-Arg acting as a Molecule in  
Stuehr_NOS Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
L-ArgStuehr_NOS
Accession No. : 12
NOS
Pathway No. : 66
1000.0016667No
The intracellular concentrations are atleast 100 uM.

L-Arg acting as a Substrate in a reaction in  
Stuehr_NOS Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
arg_bind_nNOSStuehr_NOS
Accession No. : 12
NOS
Pathway No. : 66
0.5
(uM^-1 s^-1)
81
(s^-1)
Kd(bf) = 162(uM)-Substrate
Ca-CaM_nNOS
L-Arg

Product
FeIII
From Stuehr et al., Biochem, 1999, 38(38):12446-12451. Rates used as it is from their results.



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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