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Molecule Parameter List for 5prime_GMP

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
5prime_GMP participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000100

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
Kuroda_GC18Pathway
SGC 
This model of sGC is based on the paper by Kuroda S. et al. J Neurosci. (2001) 21(15):5693-702. This models features the activation of sGC by NO, synthesis of cGMP, activity of PKG and PP2A in the synapse. The rates and concentrations have been taken from published literature.

5prime_GMP acting as a Molecule in  
Kuroda_GC Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
5prime_GMPKuroda_GC
Accession No. : 18
SGC
Pathway No. : 88
00.0016667No

5prime_GMP acting as a Product of an Enzyme in  
Kuroda_GC Network
Enzyme Molecule /
Enzyme Activity
Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
PDE  /
kenz
Kuroda_GC
Accession No. : 18
SGC
Pathway No. : 88
23.874explicit E-S complexSubstrate
cGMP

Product
5prime_GMP
Km - 2 Vmax - 3.87 Thru personal Correspondence with Shinya Kuroda... rates initially from Turko et al., 1998, Biochem J, 329, 505-510 ..