  |  Kuroda_GC |     | 
 
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 Accession information for Kuroda_GC (Accession Number 18)
 Reaction Scheme
  
  Accession Basic Parameters
  
  |  Name  |             Kuroda_GC |   
  |  Accession Type  |   Pathway |  
  |  Transcriber  |      Sudhir Sivakumaran, NCBS |  
  |  Developer  |        Shinya Kuroda, Nicolas Schweighofer and Mitsuo Kawato. |  
  |  Entry Date (YYYY-MM-DD) |        2001-12-24 00:00:00 |  
  |  Species  |          Generic mammalian |  
  |  Tissue  |           Neuronal |  
  |  Cell Compartment  | Synapse |  
  |  Source  |           Kuroda S. et al. J Neurosci. (2001) 21(15):5693-702. ( peer-reviewed publication ) |  
  |  Methodology  |      Quantitative match to experiments |  
  |  Model Implementation  | Exact GENESIS implementation |  
  |  Model Validation  | Approximates orginal data |  
   |  Notes |             This model of sGC is based on the paper by Kuroda S. et al. J Neurosci. (2001) 21(15):5693-702. This models features the activation of sGC by NO, synthesis of cGMP, activity of PKG and PP2A in the synapse. The rates and concentrations have been taken from published literature. |  
   
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