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Molecule Parameter List for inact_cap_entry

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
inact_cap_entry participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • NonOsc_Ca_
    IP3metabolism
  • 23Network
    MIPP CaMKII CaM 
    PKC IP3-3K CaRegulation 
    Gq PLCbeta 134_dephos 
    145_dephos IP4-system IHP-system 
    1345_dephos 
    This network models detailed metabolism of Ins(145)P3, integrated with GPCR mediated PLCbeta activation and Ca release by the InsP3 receptor in the neuron. The calcium response is non-oscillatory. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316.

    inact_cap_entry acting as a Molecule in  
    NonOsc_Ca_IP3metabolism Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    inact_cap_entry
  • NonOsc_Ca_
    IP3metabolism

    Accession No. : 23
  • CaRegulation
    Pathway No. : 110
    01000No
    represents the portion of the capacitative-Ca entry channel which is blocked when there is lots of Ca sequestered in the stores

    inact_cap_entry acting as a Product in a reaction in  
    NonOsc_Ca_IP3metabolism Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • inactivate_cap_
    Ca
  • NonOsc_Ca_
    IP3metabolism

    Accession No. : 23
  • CaRegulation
    Pathway No. : 110
    0
    (#^-2 s^-1)
    1
    (s^-1)
    Not applicable**-Substrate
    Ca-sequester
    Ca-sequester
  • capacitive_Ca_
    entry*


    Product
    inact_cap_entry
  • The Kd is set at about 3 uM so that at resting Ca the capacitative Ca entry is almost blocked. A 2nd order response makes the response steep.
    ** This is a trasport reation between compartments of different volumes. Therefore Kd is not applicable. Please Note Kf, Kb units are in number of molecules instead of concentration



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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