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Molecule Parameter List for IP2_3pase2

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

IP2_3pase2 participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	1	0	0	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
NonOsc_Ca_ IP3metabolism	23	Network	MIPP,  CaMKII,  CaM,   PKC,  IP3-3K,  CaRegulation,   Gq,  PLCbeta,  134_dephos,   145_dephos,  IP4-system,  IHP-system,   1345_dephos
This network models detailed metabolism of Ins(145)P3, integrated with GPCR mediated PLCbeta activation and Ca release by the InsP3 receptor in the neuron. The calcium response is non-oscillatory. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316.

IP2_3pase2 acting as a Molecule in  NonOsc_Ca_IP3metabolism Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
IP2_3pase2	NonOsc_Ca_ IP3metabolism Accession No. : 23	134_dephos Pathway No. : 113	0.0094	1000	No
from Caldwell et al, JBC 266(27); 1991: 18378-86 enzyme is a heterodimer with one catalystic subunit and one regulatory 78 kDa subunit

IP2_3pase2 acting as an Enzyme in  NonOsc_Ca_IP3metabolism Network

Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
IP2_3pase2 / ip2_3pase2	NonOsc_Ca_ IP3metabolism Accession No. : 23	134_dephos Pathway No. : 113	3.70001	39.2	4	explicit E-S complex	Substrate IP2(13) Product IP1(1)
from Caldwell et al, JBC 266; 1991