| 
 
Enter a Search String |  |  Special character and space not allowed in the query term.
          Search string should be at least 2 characters long. |      
 
 
Molecule Parameter List for IP2_3pase1  |  The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.  The text color of a molecule is highlighted by   color. |  | Statistics | 
| IP2_3pase1 participated as | Molecule | Sum total of | Enzyme | Substrate of an  enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |  | No. of occurrences | 1 | 0 | 1 | 0 | 0 | 0 | 0 |  
  Accession and Pathway Details |  |
 
 | Accession Name | Accession No. | Accession Type | Pathway Link |  NonOsc_Ca_ IP3metabolism | 23 | Network |  MIPP,  CaMKII,  CaM,   PKC,  IP3-3K,  CaRegulation,   Gq,  PLCbeta,  134_dephos,   145_dephos,  IP4-system,  IHP-system,   1345_dephos  |  | This network models detailed metabolism of Ins(145)P3, integrated with GPCR mediated PLCbeta activation and Ca release by the InsP3 receptor in the neuron. The calcium response is non-oscillatory. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. |  
  IP2_3pase1 acting as  a Molecule in  NonOsc_Ca_IP3metabolism Network
 | Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered |  | IP2_3pase1 | NonOsc_Ca_ IP3metabolism Accession No. : 23 | 134_dephos Pathway No. : 113 | 0.0038 | 1000 | No |  |   from Caldwell et al, JBC 266(27); 1991: 18378-86 Enzyme is a homodimer with two catalytic subunits. Conc of enzyme increased 2 times from 1.9 nM to account for two monomeric subunit pools  |  
  IP2_3pase1 acting as  an Enzyme in  NonOsc_Ca_IP3metabolism Network
 Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents |  IP2_3pase1 / ip2_3pase1
  | NonOsc_Ca_ IP3metabolism Accession No. : 23 | 134_dephos Pathway No. : 113 | 0.799992 | 117.33 | 4 | explicit E-S complex | Substrate IP2(13)
  Product IP1(1)
  |  |   from Caldwell et al, JBC 266; 1991 enzyme activity was assayed for the monomeric form of the enzyme |   
  
 
  | Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR   This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |   
  
 |