Enter a Search String |
| Special character and space not allowed in the query term. Search string should be at least 2 characters long. |
Molecule Parameter List for G-GDP | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| G-GDP participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 0 | 0 | 0 | 0 | 3 | 1 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| fig4_synapse | 3 | Network | Shared_Object_fig4_synapse, PKC, PLA2, PLCbeta, Gq, MAPK, Ras, CaMKII, CaM, PP1, PP2B, PKA, AC |
| This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper. Demonstration script files for generating the figures in the paper, including figure 4, are available here. | |||
G-GDP acting as a Molecule in fig4_synapse Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| G-GDP | fig4_synapse Accession No. : 3 | Gq Pathway No. : 23 | 1 | 1000 | No | |
G-GDP acting as a Substrate in a reaction in fig4_synapse Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | |
| 1 | Basal-Act-G | fig4_synapse Accession No. : 3 | Gq Pathway No. : 23 | 0.0001 (s^-1) | 0 (uM^-1 s^-1) | - | - | Substrate G-GDP Product BetaGamma G*GTP |
| 2 | Rec-Glu-bind-Gq | fig4_synapse Accession No. : 3 | Gq Pathway No. : 23 | 0.006 (uM^-1 s^-1) | 0.0001 (s^-1) | Kd(bf) = 0.0167(uM) | - | Substrate G-GDP Rec-Glu Product Rec-Glu-Gq |
| 3 | Rec-bind-Gq | fig4_synapse Accession No. : 3 | Gq Pathway No. : 23 | 0.6 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 1.6667(uM) | - | Substrate G-GDP mGluR Product Rec-Gq |
G-GDP acting as a Product in a reaction in fig4_synapse Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
| Trimerize-G | fig4_synapse Accession No. : 3 | Gq Pathway No. : 23 | 6 (uM^-1 s^-1) | 0 (s^-1) | - | - | Substrate BetaGamma G*GDP Product G-GDP |