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Accession Type:
Network
fig4_synapse
Shared_Object_
fig4_synapse
PKC
PLA2
PLCbeta
Gq
MAPK
Ras
CaMKII
CaM
PP1
PP2B
PKA
AC

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Accession information for fig4_synapse (Accession Number 3)

Reaction Scheme

Accession Basic Parameters

Name fig4_synapse
Accession Type Network
Transcriber Upinder S. Bhalla, NCBS
Developer Upinder S. Bhalla, NCBS
Entry Date (YYYY-MM-DD) 2001-11-07
Species Generic mammalian
Tissue Neuronal
Cell Compartment Synapse
Source Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )
Methodology Quantitative match to experiments, Qualitative, Hypothetical
Model Implementation Exact GENESIS implementation
Model Validation Approximates orginal data, Quantitatively predicts new data
Notes This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper.
Demonstration script files for generating the figures in the paper, including figure 4, are available here.

Conversion formats

FormatFile
Native Format (GENESIS format)    acc3.g   
GENESIS Format (Annotated version)    Anno_acc3.g   



Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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