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Molecule Parameter List for mGluR | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| mGluR participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 0 | 0 | 0 | 0 | 2 | 0 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| fig4_synapse | 3 | Network | Shared_Object_fig4_synapse, PKC, PLA2, PLCbeta, Gq, MAPK, Ras, CaMKII, CaM, PP1, PP2B, PKA, AC |
| This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper. Demonstration script files for generating the figures in the paper, including figure 4, are available here. | |||
mGluR acting as a Molecule in fig4_synapse Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| mGluR | fig4_synapse Accession No. : 3 | Gq Pathway No. : 23 | 0.3 | 1000 | No | |
mGluR acting as a Substrate in a reaction in fig4_synapse Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | |
| 1 | fig4_synapse Accession No. : 3 | Gq Pathway No. : 23 | 16.8 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 0.5952(uM) | - | Substrate Glu mGluR Product Rec-Glu | |
| 2 | Rec-bind-Gq | fig4_synapse Accession No. : 3 | Gq Pathway No. : 23 | 0.6 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 1.6667(uM) | - | Substrate G-GDP mGluR Product Rec-Gq |