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Molecule Parameter List for CaMCa2-CANAB | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| CaMCa2-CANAB participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 1 | 0 | 0 | 0 | 0 | 1 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| fig4_synapse | 3 | Network | Shared_Object_fig4_synapse, PKC, PLA2, PLCbeta, Gq, MAPK, Ras, CaMKII, CaM, PP1, PP2B, PKA, AC |
| This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper. Demonstration script files for generating the figures in the paper, including figure 4, are available here. | |||
CaMCa2-CANAB acting as a Molecule in fig4_synapse Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| CaMCa2-CANAB | fig4_synapse Accession No. : 3 | PP2B Pathway No. : 29 | 0 | 1000 | No | |
CaMCa2-CANAB acting as a Summed Molecule in fig4_synapse Network
| Accession Name | Pathway Name | Target | Input |
| fig4_synapse Accession No. : 3 | fig4_synapse Pathway No. : 19 | CaM(Ca)n-CaNAB | CaMCa4-CaNAB CaMCa3-CaNAB CaMCa2-CANAB |
CaMCa2-CANAB acting as a Product in a reaction in fig4_synapse Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
AB | fig4_synapse Accession No. : 3 | PP2B Pathway No. : 29 | 0.24 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 4.1667(uM) | - | Substrate CaM-TR2-Ca2 CaNAB-Ca4 Product CaMCa2-CANAB |