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Molecule Parameter List for Ca35-Calseq

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Ca35-Calseq participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000011

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Osc_Ca_
    IP3metabolism
    		• 32Network
    MIPP,  CaMKII,  CaM,  
    PKC,  IP3-3K,  Gq,  
    PLCbeta,  134_dephos,  145_dephos,  
    IP4-system,  IHP-system,  1345_dephos,  
    CaRegulation,  Othmer-Tang-model 
    This network models an oscillatory calcium response to GPCR mediated PLCbeta activation, alongwith detailed InsP3 metabolism in the neuron. It is similar to the Osc_Ca_IP3metab model (accession 24) except that some enzymes in the InsP3 metabolism network have been modified to have reversible kinetics rather than Michaelis-Menten kinetics. The modified enzymes belong to the groups: IP4-system, IP3-3K, 145_dephos and 134_dephos. Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316.

    Ca35-Calseq acting as a Molecule in      Osc_Ca_IP3metabolism Network
    NameAccession NamePathway NameInitial Conc.
    (uM)    		Volume
    (fL)    		Buffered
    Ca35-Calseq
  • Osc_Ca_
    IP3metabolism
    Accession No. : 32
    		• CaRegulation
    Pathway No. : 170    		0160No
    Calsequestrin with 35 Ca molecules bound

    Ca35-Calseq acting as a Substrate in a reaction in      Osc_Ca_IP3metabolism Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    Ca40-bind-Cal
  • Osc_Ca_
    IP3metabolism
    Accession No. : 32
    		• CaRegulation
    Pathway No. : 170    		0.0005
    (uM^-5 s^-1)    		1
    (s^-1)    		--Substrate
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca35-Calseq

    Product
    Ca40-Cal
    There are actually 5 Ca-sequester substrates for this reaction, along with Ca35-Cal. Due to system limitations only four are entered.

    Ca35-Calseq acting as a Product in a reaction in      Osc_Ca_IP3metabolism Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    Ca35-bind-Cal
  • Osc_Ca_
    IP3metabolism
    Accession No. : 32
    		• CaRegulation
    Pathway No. : 170    		0.0005
    (uM^-5 s^-1)    		1
    (s^-1)    		--Substrate
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca-sequester
    Ca30-Calseq

    Product
    Ca35-Calseq
    There are actually 5 Ca-sequester substrates for this reaction, along with Ca30-Cal. Due to system limitations only four are entered.


    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.