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Molecule Parameter List for Total_CaMKII | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
| Total_CaMKII participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction | | No. of occurrences | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Accession and Pathway Details | |
Total_CaMKII acting as a Molecule in CaMKII Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | Total_CaMKII | CaMKII
Accession No. : 33 | CaMKII
Pathway No. : 174 | 127.325 | 0.1309 | No | | This is not directly in the Holmes model. It is a trick used in GENESIS/Kinetikit to scale activity down for intramolecular reactions. Here it is used to scale the autophosph reactions such that only neighboring subunits will phosphorylate each other. This is done by scaling down the actual conc (in the enzyme parent, Tot-active-CaMKII) by the total conc such that instead of a conc, we the fraction of nearby subunits that will be active. Note that this conc of 10000 CaMKII subunits is 10 times the true conc, since only 1/10 of the molecules are neighboring molecules. |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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