DOQCS database

NCBS Home page

Accession List

Pathway List

Authorized Users

Help

News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.

Molecule Parameter List for L

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

L participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	0	0	0	1	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
MAPK_Asthagiri_ no_fb	44	Pathway	MAPK_Asthagiri_no_fb
This is a complex model to examine mechanisms that govern MAPK pathway dynamics in Chinese hamster ovary (CHO) cell lines. This model simulates the results as per the figure 4 of the paper by Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39.

L acting as a Molecule in MAPK_Asthagiri_no_fb Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
L	MAPK_Asthagiri_ no_fb Accession No. : 44	MAPK_Asthagiri_ no_fb Pathway No. : 192	0.03	390	Yes
L CoInit = buffered at 0.03 uM from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39

L acting as a Substrate in a reaction in MAPK_Asthagiri_no_fb Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
L-bind-R	MAPK_Asthagiri_ no_fb Accession No. : 44	MAPK_Asthagiri_ no_fb Pathway No. : 192	0.1666 (uM^-1 s^-1)	0.005 (s^-1)	Kd(bf) = 0.03(uM)	-	Substrate L R Product C
Kf = 10^7/M-1 min-1 and Kr is 0.3 min-1 from Anand R. Asthagiri and Douglas A. Lauffenburger (2001 Mar-Apr) Biotechnol Prog. 17(2):227-39

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.