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Molecule Parameter List for ATP

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

ATP participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	0	5	0	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
MAPK_network_ 2003	50	Network	Shared_Object_MAPK_network_2003,  PKC,  PLA2,   PLCbeta,  Gq,  MAPK,   Ras,  EGFR,  Sos,   PLC_g,  CaMKII,  CaM,   PP1,  PP2B,  PKA,   AC
This is a network model of many pathways present at the neuronal synapse. The network has properties of temporal tuning as well as steady-state computational properties. In its default form the network is bistable.Bhalla US Biophys J. 2004 Aug;87(2):745-53

ATP acting as a Molecule in  MAPK_network_2003 Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
ATP	MAPK_network_ 2003 Accession No. : 50	AC Pathway No. : 221	5000	1000	Yes
ATP is present in all cells between 2 and 10 mM. See Lehninger.

ATP acting as a Substrate for an Enzyme in  MAPK_network_2003 Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	AC1-CaM  / kenz	MAPK_network_ 2003 Accession No. : 50	AC Pathway No. : 221	20	18	4	Classical Michaelis-Menten V = Etot.S.Kcat/Km+S	Substrate ATP Product cAMP
2	AC2*  / kenz	MAPK_network_ 2003 Accession No. : 50	AC Pathway No. : 221	20.1149	7	4	Classical Michaelis-Menten V = Etot.S.Kcat/Km+S	Substrate ATP Product cAMP
	Reduced Km to match expt data for basal activation of AC2 by PKC. Now k1 = 2.9e-6, k2 = 72, k3 = 18
3	AC2-Gs  / kenz	MAPK_network_ 2003 Accession No. : 50	AC Pathway No. : 221	20	18	4	Classical Michaelis-Menten V = Etot.S.Kcat/Km+S	Substrate ATP Product cAMP
4	AC1-Gs  / kenz	MAPK_network_ 2003 Accession No. : 50	AC Pathway No. : 221	20	18	4	Classical Michaelis-Menten V = Etot.S.Kcat/Km+S	Substrate ATP Product cAMP
5	AC2*-Gs  / kenz	MAPK_network_ 2003 Accession No. : 50	AC Pathway No. : 221	60	54	4	Classical Michaelis-Menten V = Etot.S.Kcat/Km+S	Substrate ATP Product cAMP