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Molecule Parameter List for ATP

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
ATP participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1005000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • MAPK_network_
    2003
  • 50Network
    Shared_Object_MAPK_network_2003 PKC PLA2 
    PLCbeta Gq MAPK 
    Ras EGFR Sos 
    PLC_g CaMKII CaM 
    PP1 PP2B PKA 
    AC 
    This is a network model of many pathways present at the neuronal synapse. The network has properties of temporal tuning as well as steady-state computational properties. In its default form the network is bistable.Bhalla US Biophys J. 2004 Aug;87(2):745-53

    ATP acting as a Molecule in  
    MAPK_network_2003 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    ATP
  • MAPK_network_
    2003

    Accession No. : 50
  • AC
    Pathway No. : 221
    50001000Yes
    ATP is present in all cells between 2 and 10 mM. See Lehninger.

    ATP acting as a Substrate for an Enzyme in  
    MAPK_network_2003 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1AC1-CaM  /
    kenz
  • MAPK_network_
    2003

    Accession No. : 50
  • AC
    Pathway No. : 221
    20184Classical Michaelis-Menten
    V = Etot.S.Kcat/Km+S
    Substrate
    ATP

    Product
    cAMP
    2AC2*  /
    kenz
  • MAPK_network_
    2003

    Accession No. : 50
  • AC
    Pathway No. : 221
    20.114974Classical Michaelis-Menten
    V = Etot.S.Kcat/Km+S
    Substrate
    ATP

    Product
    cAMP
        Reduced Km to match expt data for basal activation of AC2 by PKC. Now k1 = 2.9e-6, k2 = 72, k3 = 18
    3AC2-Gs  /
    kenz
  • MAPK_network_
    2003

    Accession No. : 50
  • AC
    Pathway No. : 221
    20184Classical Michaelis-Menten
    V = Etot.S.Kcat/Km+S
    Substrate
    ATP

    Product
    cAMP
    4AC1-Gs  /
    kenz
  • MAPK_network_
    2003

    Accession No. : 50
  • AC
    Pathway No. : 221
    20184Classical Michaelis-Menten
    V = Etot.S.Kcat/Km+S
    Substrate
    ATP

    Product
    cAMP
    5AC2*-Gs  /
    kenz
  • MAPK_network_
    2003

    Accession No. : 50
  • AC
    Pathway No. : 221
    60544Classical Michaelis-Menten
    V = Etot.S.Kcat/Km+S
    Substrate
    ATP

    Product
    cAMP



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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