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Molecule Parameter List for enz16

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
enz16 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1010000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • EGFR_Signaling_
    pathway
    		• 52Pathway
    EGFR 
    This model is based on the model and parameters published in paper: Quantification of Short Term Signaling by the EGFR Kholodenko et al, The J Biol Chem. , Vol 274, No. 42, Issue of October 15, pp. 30169 - 30181, 1999.
    Note: There are a few small ambiguities in the paper about initial conditions employed for obtaining the results. Thanks to Dr. Kholodenko for clarifying those ambiguities and providing the values used in the simulations:[G-S]=33.04579, [Grb]=51.95431, [SOS]=0.95421.

    enz16 acting as a Molecule in      EGFR_Signaling_pathway Network
    NameAccession NamePathway NameInitial Conc.
    (uM)    		Volume
    (fL)    		Buffered
    enz16
  • EGFR_Signaling_
    pathway
    Accession No. : 52
    		• EGFR
    Pathway No. : 223    		0.0011.6667E-6No
    Taken from Kholodenko et al 1999.

    enz16 acting as an Enzyme in      EGFR_Signaling_pathway Network
    Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    enz16 /
    r16
  • EGFR_Signaling_
    pathway
    Accession No. : 52
    		• EGFR
    Pathway No. : 223    		0.341.74Classical Michaelis-Menten
    V = Etot.S.Kcat/Km+S    		Substrate
    ShP

    Product
    Shc
    Taken from Kholodenko et al 1999.


    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.