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Parameters for EGFR (Pathway Number 223) Pathway Layout
Pathway Basic Parameters Pathway Name | EGFR | Pathway Entry Number | 223 | Accession Number | 52 | Accession Name | EGFR_Signaling_pathway | Species | Harlan Sprague Dawley rat; mammalian | Tissue | Hepatocytes | CellCompartment | Cell membrane + cytosol | Related Pathways | 8,
77,
213,
232,
319,
336,
354
| Notes | This model is based on the model and parameters published in paper: Quantification of Short Term Signaling by the EGFR Kholodenko et al, The J Biol Chem. , Vol 274, No. 42, Issue of October 15, pp. 30169 - 30181, 1999. Note: There are a few small ambiguities in the paper about initial conditions employed for obtaining the results. Thanks to Dr. Kholodenko for clarifying those ambiguities and providing the values used in the simulations:[G-S]=33.04579, [Grb]=51.95431, [SOS]=0.95421.
| Statistics Conversion formatThis pathway is part of accession 52 and is completely specified in the file acc52.g. There is no separate files for just this pathway. |
Pathway Detail Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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