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Molecule Parameter List for MYpYpYp | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics | Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | Chemotaxis | 55 | Pathway | Chemotaxis | All parameters used are from the .BCT files for BCT1.1 provided by Matthew Levin from the Computational Biology Group in the Department of Zoology at the University of Cambridge.Bias does not reach 0.7, there is a lag in the response of bias to the 5 sec 1 uM Aspartate pulse as shown by Bray et al. Mol.Biol.Cell (1993) 4(5): 469-482. The June 2003 version of the BCT program is BCT4.3 and is available at the computational biology site of the Zoology department at Cambridge University. |
MYpYpYp acting as a Molecule in Chemotaxis Network
Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | MYpYpYp | Chemotaxis Accession No. : 55 | Chemotaxis Pathway No. : 226 | 0.0004 | 1.41 | No | MYpYpYp = 4.47e-10 M = 4.47e-4 uM As per Signal 26 in 1SIG_B.BCT provided by Matthew Levin Cell volume = 1.41e-15 L Table 1 pp.474 Bray et al 1993, Mol.Biol.Cell 4: 469-482 |
MYpYpYp acting as a Summed Molecule in Chemotaxis Network
| Accession Nane | Pathway Name | Target | Input | 1 | Chemotaxis Accession No. : 55 | Chemotaxis Pathway No. : 226 | Denominator | MYpYp MYpYpYp MYpYpYpYp MYp Motor
| | Denominator value to calculate bias as stated on pp.471
Bias = [M + MYp]/[M + MYp + MYpYp + MYpYpYp + MYpYpYpYp]
Bray et al 1993, Mol.Biol.Cell 4: 469-482 | 2 | Chemotaxis Accession No. : 55 | Chemotaxis Pathway No. : 226 | CW_rotation | MYpYpYpYp MYpYpYp
| | Sum total of MYpYpYp and MYpYpYpYp which is responsible for CW rotation of the flagella Bray et al 1993, Mol.Biol.Cell 4: 469-482 |
MYpYpYp acting as a Substrate in a reaction in Chemotaxis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | Complexing[6] | Chemotaxis Accession No. : 55 | Chemotaxis Pathway No. : 226 | 2006.97 (uM^-1 s^-1) | 5.5 (s^-1) | Kd(bf) = 0.0027(uM) | - | Substrate CheYp MYpYpYp
Product MYpYpYpYp
| CheYp complexes with MYpYpYp Kf = 20.07/Set_Yp = 20.07/1e-08 /sec/M = 20.07e+2 /sec/uM Kb = 5.5 /sec As per EXEC.C provided by Matthew Levin Bray et al 1993, Mol.Biol.Cell 4: 469-482 |
MYpYpYp acting as a Product in a reaction in Chemotaxis Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | Complexing[5] | Chemotaxis Accession No. : 55 | Chemotaxis Pathway No. : 226 | 693.999 (uM^-1 s^-1) | 5.1 (s^-1) | Kd(bf) = 0.0073(uM) | - | Substrate CheYp MYpYp
Product MYpYpYp
| Tar-Ni-CheW-CheA complex TnWA = 0 M As per Signal 15 in 1SIG.BCT provided by Matthew Levin Cell volume = 1.41e-15 L Table 1 pp.474 Bray et al 1993, Mol.Biol.Cell 4: 469-482 |
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