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Molecule Parameter List for PP1-active | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
| PP1-active participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction | | No. of occurrences | 1 | 0 | 2 | 0 | 0 | 0 | 0 |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | simple_AMPAR_
traff_model2 | 61 | Network |
Shared_Object_simple_AMPAR_traff_model2, Membrane, Internal | | This is a highly simplified model of the AMPAR trafficking cycle that exhibits bistability. It is model 2 from Hayer and Bhalla, PLoS 2005. Its main purpose it to illustrate how the bistability arises. |
PP1-active acting as a Molecule in simple_AMPAR_traff_model2 Network
PP1-active acting as an Enzyme in simple_AMPAR_traff_model2 Network
| | Enzyme Molecule /
Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | | 1 | PP1-active /
PP1
| simple_AMPAR_
traff_model2
Accession No. : 61 | Membrane
Pathway No. : 255 | 0.999989 | 0.35 | 4 | explicit E-S complex | Substrate
MR*
Product
MR
| | | Note that Km is halved from 2 to 1, as compared to original detailed model. This is because each substrate represents two subunits of the original detailed model. | | 2 | PP1-active /
PP1[1]
| simple_AMPAR_
traff_model2
Accession No. : 61 | Membrane
Pathway No. : 255 | 0.999989 | 0.35 | 4 | explicit E-S complex | Substrate
MR**
Product
MR*
| | | Note halving of Km from 2 to 1. See also notes for internal-PKA-act. Basically, the enzyme must act on two substrate subunits which are lumped in the current simplification of the original detailed model. We thank an anonymous reviewer for pointing this out. |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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