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Molecule Parameter List for tot_autonomous_CaMKII

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
tot_autonomous_CaMKII participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1220000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • CaMKII_noPKA_
    model3
  • 62Network
    Shared_Object_CaMKII_noPKA_model3 CaMKII CaM 
    PP1 PP2B PP1_PSD 
    This is the model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 does not include the full PKA regulatory pathway, and instead has a predefined initial amount of active PKA.

    tot_autonomous_CaMKII acting as a Molecule in  
    CaMKII_noPKA_model3 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    tot_autonomous_CaMKII
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • CaMKII
    Pathway No. : 258
    20.09No

    tot_autonomous_CaMKII acting as a Summed Molecule in  
    CaMKII_noPKA_model3 Network
     Accession NanePathway NameTargetInput
    1
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • CaMKII
    Pathway No. : 258
    tot_autonomous_CaMKIICaMKII-thr286
    CaMKII***
  • basal_CaMKII_
    cyt

  • 2
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • Shared_Object_
    CaMKII_noPKA_
    model3

    Pathway No. : 257
  • act_CaMKII_cyttot_CaM_CaMKII
  • tot_autonomous_
    CaMKII


  • tot_autonomous_CaMKII acting as an Enzyme in  
    CaMKII_noPKA_model3 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1
  • tot_autonomous_
    CaMKII
     /
    auton_305
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • CaMKII
    Pathway No. : 258
    35064explicit E-S complexSubstrate
    CaMKII-thr286

    Product
    CaMKII***
        See Hanson and Schulman again, for afterburst rates of phosph.
    2
  • tot_autonomous_
    CaMKII
     /
    auton_286
  • CaMKII_noPKA_
    model3

    Accession No. : 62
  • CaMKII
    Pathway No. : 258
    349.9870.54explicit E-S complexSubstrate
    CaMKII-CaM

    Product
  • CaMKII-thr286*-C
    aM




  • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.