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Molecule Parameter List for tot-auto-PSD | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| tot-auto-PSD participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 2 | 3 | 0 | 0 | 0 | 0 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
model3 | 62 | Network | Shared_Object_CaMKII_noPKA_model3, CaMKII, CaM, PP1, PP2B, PP1_PSD |
| This is the model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 does not include the full PKA regulatory pathway, and instead has a predefined initial amount of active PKA. | |||
tot-auto-PSD acting as a Molecule in CaMKII_noPKA_model3 Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| tot-auto-PSD | model3 Accession No. : 62 | CaMKII_noPKA_ model3 Pathway No. : 257 | 2 | 0.01 | No | |
tot-auto-PSD acting as a Summed Molecule in CaMKII_noPKA_model3 Network
| Accession Nane | Pathway Name | Target | Input | |
| 1 | model3 Accession No. : 62 | CaMKII_noPKA_ model3 Pathway No. : 257 | tot-auto-PSD | D CaMKII***-PSD PSD |
| 2 | model3 Accession No. : 62 | CaMKII_noPKA_ model3 Pathway No. : 257 | actCaMKII-PSD | M-PSD CaMKII-CaM-PSD tot-auto-PSD |
tot-auto-PSD acting as an Enzyme in CaMKII_noPKA_model3 Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | |
| 1 | tot-auto-PSD / auton-305-PSD | model3 Accession No. : 62 | CaMKII_noPKA_ model3 Pathway No. : 257 | 500 | 6 | 4 | explicit E-S complex | Substrate D Product CaMKII***-PSD |
| 2 | tot-auto-PSD / auton-286-PSD | model3 Accession No. : 62 | CaMKII_noPKA_ model3 Pathway No. : 257 | 500.002 | 0.5 | 4 | explicit E-S complex | Substrate CaMKII-CaM-PSD Product M-PSD |
| 3 | tot-auto-PSD / auton-autoph | model3 Accession No. : 62 | CaMKII_noPKA_ model3 Pathway No. : 257 | 500.005 | 2 | 4 | explicit E-S complex | Substrate CaMKII-PSD Product D |
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