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Molecule Parameter List for CaMKII*** | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics | Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | AMPAR_CaMKII_ strong_coupling | 64 | Network | Shared_Object_AMPAR_CaMKII_strong_coupling, CaMKII, CaM, PP1, AMPAR_memb, PP2B, PKA, AC, PP1_PSD, AMPAR | This is a model of tight coupling between the AMPAR trafficking bistability, and the CaMKII autophosphorylation bistability. In this model, the CaMKII activity is self sustaining only when AMPAR is turned on. Further, CaMKII turns on when AMPAR is turned on. |
CaMKII*** acting as a Molecule in AMPAR_CaMKII_strong_coupling Network
Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | CaMKII*** | AMPAR_CaMKII_ strong_coupling Accession No. : 64 | CaMKII Pathway No. : 272 | 0 | 0.09 | No | From Hanson and Schulman, the CaMKII does a lot of autophosphorylation just after the CaM is released. This prevents further CaM binding and renders the enzyme quite independent of Ca. |
CaMKII*** acting as a Summed Molecule in AMPAR_CaMKII_strong_coupling Network
CaMKII*** acting as a Substrate for an Enzyme in AMPAR_CaMKII_strong_coupling Network
CaMKII*** acting as a Product of an Enzyme in AMPAR_CaMKII_strong_coupling Network
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