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Accession Type:
Network
AMPAR_CaMKII_
strong_coupling
Shared_Object_
AMPAR_CaMKII_
strong_coupling
CaMKII
CaM
PP1
AMPAR_memb
PP2B
PKA
AC
PP1_PSD
AMPAR

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Accession information for AMPAR_CaMKII_strong_coupling (Accession Number 64)

Reaction Scheme

Accession Basic Parameters

Name AMPAR_CaMKII_strong_coupling
Accession Type Network
Transcriber Upinder S. Bhalla, NCBS
Developer Arnold Hayer and Upinder S. Bhalla, NCBS
Entry Date (YYYY-MM-DD) 2005-07-19
Species General Mammalian
Tissue Neuronal
Cell Compartment Synaptic Spine, Postsynaptic Density
Source Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )
Methodology Quantitative match to experiments, Qualitative
Model Implementation Exact GENESIS implementation
Model Validation Replicates original data , Approximates original data
Notes This is a model of tight coupling between the AMPAR trafficking bistability, and the CaMKII autophosphorylation bistability. In this model, the CaMKII activity is self sustaining only when AMPAR is turned on. Further, CaMKII turns on when AMPAR is turned on.

Conversion formats

FormatFile
Native Format (GENESIS format)    acc64.g   
MATLAB format    acc64.m   
SBML format    acc64.xml   



Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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