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Molecule Parameter List for A845_B831

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

A845_B831 participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	2	3	0	7	7	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
AMPAR_CaMKII_ strong_coupling	64	Network	Shared_Object_AMPAR_CaMKII_strong_coupling, CaMKII, CaM, PP1, AMPAR_memb, PP2B, PKA, AC, PP1_PSD, AMPAR
This is a model of tight coupling between the AMPAR trafficking bistability, and the CaMKII autophosphorylation bistability. In this model, the CaMKII activity is self sustaining only when AMPAR is turned on. Further, CaMKII turns on when AMPAR is turned on.

A845*_B831* acting as a Molecule in AMPAR_CaMKII_strong_coupling Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
A845_B831	AMPAR_CaMKII_ strong_coupling Accession No. : 64	AMPAR Pathway No. : 280	0	0.09	No

A845_B831	AMPAR_CaMKII_ strong_coupling Accession No. : 64	AMPAR_memb Pathway No. : 275	0	0.01	No

A845*_B831* acting as a Summed Molecule in AMPAR_CaMKII_strong_coupling Network

	Accession Nane	Pathway Name	Target	Input
1	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	I_845-P	A831845_B831* A845_B831 A831845_B A845_B A831_B831845 A_B831845 A831_B845 A_B845*
2	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	Ser845-P	A845_B A831845_B A845_B831* A831845_B831* A_B845* A831_B845 A_B831845 A831_B831845*
3	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	Ser831-P	A831845_B845* A845_B831845* A831_B845 A_B831845 A831845_B A845_B831 A831_B A_B831

A845*_B831* acting as a Substrate for an Enzyme in AMPAR_CaMKII_strong_coupling Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PKA-active / PKA[30]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	7.50021	6	4	explicit E-S complex	Substrate A845_B831 Product A845_B831845*
2	PKA-active / PKA[9]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	7.50021	6	4	explicit E-S complex	Substrate A845_B831 Product A845_B831845*
3	actCaMKII-PSD / CaMKII[10]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	90.0006	0.5	4	explicit E-S complex	Substrate A845_B831 Product A831845_B831*
4	PP1-active_PSD / PP1[15]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	0.971451	0.17	4	explicit E-S complex	Substrate A845_B831 Product A_B831*
5	PP1-active_PSD / PP1[22]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	2.00005	0.35	4	explicit E-S complex	Substrate A845_B831 Product A845*_B
6	CaM_Ca_n-CaNAB / PP2B[19]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	4.97061	2	4	explicit E-S complex	Substrate A845_B831 Product A_B831*
7	CaM_Ca_n-CaNAB / PP2B[11]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	4.97061	2	4	explicit E-S complex	Substrate A845_B831 Product A_B831*

A845*_B831* acting as a Product of an Enzyme in AMPAR_CaMKII_strong_coupling Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PKA-active / PKA[18]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	7.50021	6	4	explicit E-S complex	Substrate A_B831* Product A845_B831
2	PKA-active / PKA[11]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	7.50021	6	4	explicit E-S complex	Substrate A_B831* Product A845_B831
3	actCaMKII-PSD / CaMKII[6]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	90.0006	0.5	4	explicit E-S complex	Substrate A845_B Product* A845_B831
4	PP1-active_PSD / PP1[13]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	0.971451	0.17	4	explicit E-S complex	Substrate A845_B831845* Product A845_B831
5	PP1-active_PSD / PP1[26]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	2.00005	0.35	4	explicit E-S complex	Substrate A831845_B831* Product A845_B831
6	CaM_Ca_n-CaNAB / PP2B[31]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	4.97061	2	4	explicit E-S complex	Substrate A845_B831845* Product A845_B831
7	CaM_Ca_n-CaNAB / PP2B[9]	AMPAR_CaMKII_ strong_coupling Accession No. : 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. : 271	4.97061	2	4	explicit E-S complex	Substrate A845_B831845* Product A845_B831

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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Molecule Parameter List for A845*_B831*

Molecule Parameter List for A845_B831