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Molecule Parameter List for tot_autonomous_CaMKII

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
tot_autonomous_CaMKII participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1220000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • AMPAR_CaMKII_
    strong_coupling
  • 64Network
    Shared_Object_AMPAR_CaMKII_strong_coupling CaMKII CaM 
    PP1 AMPAR_memb PP2B 
    PKA AC PP1_PSD 
    AMPAR 
    This is a model of tight coupling between the AMPAR trafficking bistability, and the CaMKII autophosphorylation bistability. In this model, the CaMKII activity is self sustaining only when AMPAR is turned on. Further, CaMKII turns on when AMPAR is turned on.

    tot_autonomous_CaMKII acting as a Molecule in  
    AMPAR_CaMKII_strong_coupling Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    tot_autonomous_CaMKII
  • AMPAR_CaMKII_
    strong_coupling

    Accession No. : 64
  • CaMKII
    Pathway No. : 272
    20.09No

    tot_autonomous_CaMKII acting as a Summed Molecule in  
    AMPAR_CaMKII_strong_coupling Network
     Accession NanePathway NameTargetInput
    1
  • AMPAR_CaMKII_
    strong_coupling

    Accession No. : 64
  • CaMKII
    Pathway No. : 272
    tot_autonomous_CaMKIICaMKII-thr286
    CaMKII***
  • basal_CaMKII_
    cyt

  • 2
  • AMPAR_CaMKII_
    strong_coupling

    Accession No. : 64
  • Shared_Object_
    AMPAR_CaMKII_
    strong_coupling

    Pathway No. : 271
  • act_CaMKII_cyttot_CaM_CaMKII
  • tot_autonomous_
    CaMKII


  • tot_autonomous_CaMKII acting as an Enzyme in  
    AMPAR_CaMKII_strong_coupling Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1
  • tot_autonomous_
    CaMKII
     /
    auton_305
  • AMPAR_CaMKII_
    strong_coupling

    Accession No. : 64
  • CaMKII
    Pathway No. : 272
    35064explicit E-S complexSubstrate
    CaMKII-thr286

    Product
    CaMKII***
        See Hanson and Schulman again, for afterburst rates of phosph.
    2
  • tot_autonomous_
    CaMKII
     /
    auton_286
  • AMPAR_CaMKII_
    strong_coupling

    Accession No. : 64
  • CaMKII
    Pathway No. : 272
    349.9870.54explicit E-S complexSubstrate
    CaMKII-CaM

    Product
  • CaMKII-thr286*-C
    aM




  • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.