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Name Notes Model

Molecule Parameter List for Amino_Acids

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

Amino_Acids participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	3	0	0	3	0	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Repressilator	68	Network	Lambda-cl_gene,  Lac_gene,  TetR_gene
This is a network model termed as Repressilator in which LacI inhibit transcription of tetR which in turn inhibit transcription of Lambda phage. This model simulates the result as per the Fig 1c of the paper : Elowitz MB, Leibler S., Nature. 2000 Jan 20;403(6767):335-8.

Amino_Acids acting as a Molecule in  Repressilator Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
Amino_Acids	Repressilator Accession No. : 68	Lambda-cl_gene Pathway No. : 295	0.0006	3	Yes
Amino_Acids	Repressilator Accession No. : 68	Lac_gene Pathway No. : 296	0.0006	3	Yes
Amino_Acids	Repressilator Accession No. : 68	TetR_gene Pathway No. : 297	0.0006	3	Yes

Amino_Acids acting as a Substrate for an Enzyme in  Repressilator Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	lambda-cl_mRNA  / lambda-cl_ translation	Repressilator Accession No. : 68	Lambda-cl_gene Pathway No. : 295	0.000555595	0.167	4	Classical Michaelis-Menten V = Etot.S.Kcat/Km+S	Substrate Amino_Acids Product Lambda-cl
	Translation the lambda cl mRNA. Rates from Box 1 Elowitz, M. et al (2000) Nature 403:335-338
2	lac_mRNA  / lac_translation	Repressilator Accession No. : 68	Lac_gene Pathway No. : 296	0.000555595	0.167	4	Classical Michaelis-Menten V = Etot.S.Kcat/Km+S	Substrate Amino_Acids Product Lac
	Translation of the lac mRNA. Rates from Box 1 Elowitz, M. et al (2000) Nature 403: 335-338
3	tetR_mRNA  / tetR_ translation	Repressilator Accession No. : 68	TetR_gene Pathway No. : 297	0.000555595	0.167	4	Classical Michaelis-Menten V = Etot.S.Kcat/Km+S	Substrate Amino_Acids Product TetR
	Translation of the tetR mRNA. Rates from Box 1 Elowitz, M. et al. (2000) Nature 403:335-338