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Molecule Parameter List for Amino_Acids

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Amino_Acids participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences3003000

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
Repressilator68Network
Lambda-cl_gene Lac_gene TetR_gene 
This is a network model termed as Repressilator in which LacI inhibit transcription of tetR which in turn inhibit transcription of Lambda phage. This model simulates the result as per the Fig 1c of the paper : Elowitz MB, Leibler S., Nature. 2000 Jan 20;403(6767):335-8.

Amino_Acids acting as a Molecule in  
Repressilator Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
Amino_AcidsRepressilator
Accession No. : 68
Lambda-cl_gene
Pathway No. : 295
0.00063Yes
Amino_AcidsRepressilator
Accession No. : 68
Lac_gene
Pathway No. : 296
0.00063Yes
Amino_AcidsRepressilator
Accession No. : 68
TetR_gene
Pathway No. : 297
0.00063Yes

Amino_Acids acting as a Substrate for an Enzyme in  
Repressilator Network
 Enzyme Molecule /
Enzyme Activity
Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
1lambda-cl_mRNA  /
  • lambda-cl_
    translation
  • Repressilator
    Accession No. : 68
    Lambda-cl_gene
    Pathway No. : 295
    0.0005555950.1674Classical Michaelis-Menten
    V = Etot.S.Kcat/Km+S
    Substrate
    Amino_Acids

    Product
    Lambda-cl
        Translation the lambda cl mRNA. Rates from Box 1 Elowitz, M. et al (2000) Nature 403:335-338
    2lac_mRNA  /
    lac_translation
    Repressilator
    Accession No. : 68
    Lac_gene
    Pathway No. : 296
    0.0005555950.1674Classical Michaelis-Menten
    V = Etot.S.Kcat/Km+S
    Substrate
    Amino_Acids

    Product
    Lac
        Translation of the lac mRNA. Rates from Box 1 Elowitz, M. et al (2000) Nature 403: 335-338
    3tetR_mRNA  /
  • tetR_
    translation
  • Repressilator
    Accession No. : 68
    TetR_gene
    Pathway No. : 297
    0.0005555950.1674Classical Michaelis-Menten
    V = Etot.S.Kcat/Km+S
    Substrate
    Amino_Acids

    Product
    TetR
        Translation of the tetR mRNA. Rates from Box 1 Elowitz, M. et al. (2000) Nature 403:335-338



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