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Molecule Parameter List for Degraded_lac | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Degraded_lac participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| Repressilator | 68 | Network | Lambda-cl_gene, Lac_gene, TetR_gene |
| This is a network model termed as Repressilator in which LacI inhibit transcription of tetR which in turn inhibit transcription of Lambda phage. This model simulates the result as per the Fig 1c of the paper : Elowitz MB, Leibler S., Nature. 2000 Jan 20;403(6767):335-8. | |||
Degraded_lac acting as a Molecule in Repressilator Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| Degraded_lac | Repressilator Accession No. : 68 | Lac_gene Pathway No. : 296 | 0 | 3 | Yes | |
| Degradation product of Lac protein | ||||||
Degraded_lac acting as a Product in a reaction in Repressilator Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
| Lac_degradation | Repressilator Accession No. : 68 | Lac_gene Pathway No. : 296 | 0.0167 (s^-1) | 0 (s^-1) | - | - | Substrate Lac Product Degraded_lac |
| This reaction denotes the degradation of Lac the half life of which is ten minutes. t1/2 = 0.693/k where k denotes kf Note: Rates had to scaled by approx 1.4 to get desired levels Elowitz, M. et al. (2000) Nature 403:335-338 | |||||||