NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule Parameter List for Degraded_lac

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Degraded_lac participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
Repressilator68Network
Lambda-cl_gene Lac_gene TetR_gene 
This is a network model termed as Repressilator in which LacI inhibit transcription of tetR which in turn inhibit transcription of Lambda phage. This model simulates the result as per the Fig 1c of the paper : Elowitz MB, Leibler S., Nature. 2000 Jan 20;403(6767):335-8.

Degraded_lac acting as a Molecule in  
Repressilator Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
Degraded_lacRepressilator
Accession No. : 68
Lac_gene
Pathway No. : 296
03Yes
Degradation product of Lac protein

Degraded_lac acting as a Product in a reaction in  
Repressilator Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
Lac_degradationRepressilator
Accession No. : 68
Lac_gene
Pathway No. : 296
0.0167
(s^-1)
0
(s^-1)
--Substrate
Lac

Product
Degraded_lac
This reaction denotes the degradation of Lac the half life of which is ten minutes. t1/2 = 0.693/k where k denotes kf Note: Rates had to scaled by approx 1.4 to get desired levels Elowitz, M. et al. (2000) Nature 403:335-338



Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.