NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule Parameter List for RanBP1

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
RanBP1 participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000010

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
RanGTPase70Network
Shared_Object_RanGTPase Nucleus Cytoplasm 
This model represents a concentration gradient of RanGTP across the nuclear envelope. This gradient is generated by distribution of regulators of RanGTPase. We have taken a log linear plot of graphs generated by GENESIS and compared with the experimental graphs.

RanBP1 acting as a Molecule in  
RanGTPase Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
RanBP1RanGTPase
Accession No. : 70
Cytoplasm
Pathway No. : 306
218000No
RanBP1 RanBP1 in the cytoplasm Cytoplasmic volume = 1.8 pL = 1.8e-15 m^3 Total cytoplasmic concentration of RanBP1 = 2 uM Supplementary Table B Gorlich D et al (2003) EMBO J 22(5):1088-1100

RanBP1 acting as a Substrate in a reaction in  
RanGTPase Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
NameAccession NamePathway NameKfKbKdtauReagents
RanGTP_bindingRanGTPase
Accession No. : 70
Cytoplasm
Pathway No. : 306
18.0004
(uM^-1 s^-1)
0.0004
(s^-1)
Kd(bf) = 0(uM)-Substrate
  • GTP.Ran-cytoplas
    mic

    RanBP1

    Product
    RanBP1.RanGTP



  • Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.