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Molecule Parameter List for PKC-DAG-memb* | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | Statistics | Accession and Pathway Details | |
Accession Name | Accession No. | Accession Type | Pathway Link | Ajay_Bhalla_ 2004_Feedback_ Tuning | 78 | Network | Shared_Object_Ajay_Bhalla_2004_Feedback_Tuning, PKC, PLA2, PLCbeta, Gq, MAPK, Ras, EGFR, Sos, PLC_g, CaMKII, CaM, PP1, PP2B, PKA, AC | This model is taken from Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. This is the feedback model from Figure 8a. |
PKC-DAG-memb* acting as a Molecule in Ajay_Bhalla_2004_Feedback_Tuning Network
PKC-DAG-memb* acting as a Summed Molecule in Ajay_Bhalla_2004_Feedback_Tuning Network
PKC-DAG-memb* acting as a Product in a reaction in Ajay_Bhalla_2004_Feedback_Tuning Network
Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | PKC-DAG-to-memb | Ajay_Bhalla_ 2004_Feedback_ Tuning Accession No. : 78 | PKC Pathway No. : 348 | 1 (s^-1) | 0.1 (s^-1) | Keq = 0.1(uM) | 0.909sec | Substrate PKC-Ca-DAG
Product PKC-DAG-memb*
| Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al. |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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