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Molecule Parameter List for PKC-basal* | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | Ajay_Bhalla_
2004_Feedback_
Tuning | 78 | Network |
Shared_Object_Ajay_Bhalla_2004_Feedback_Tuning, PKC, PLA2,
PLCbeta, Gq, MAPK,
Ras, EGFR, Sos,
PLC_g, CaMKII, CaM,
PP1, PP2B, PKA,
AC | | This model is taken from Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. This is the feedback model from Figure 8a. |
PKC-basal* acting as a Molecule in Ajay_Bhalla_2004_Feedback_Tuning Network
PKC-basal* acting as a Summed Molecule in Ajay_Bhalla_2004_Feedback_Tuning Network
PKC-basal* acting as a Product in a reaction in Ajay_Bhalla_2004_Feedback_Tuning Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | PKC-basal-act | Ajay_Bhalla_
2004_Feedback_
Tuning
Accession No. : 78 | PKC
Pathway No. : 348 | 1
(s^-1) | 50
(s^-1) | Keq = 50(uM) | 0.02sec | Substrate
PKC-cytosolic
Product
PKC-basal*
| | Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher. |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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