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Molecule Parameter List for CaMK-thr306 | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | Ajay_Bhalla_
2004_Feedback_
Tuning | 78 | Network |
Shared_Object_Ajay_Bhalla_2004_Feedback_Tuning, PKC, PLA2,
PLCbeta, Gq, MAPK,
Ras, EGFR, Sos,
PLC_g, CaMKII, CaM,
PP1, PP2B, PKA,
AC | | This model is taken from Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. This is the feedback model from Figure 8a. |
CaMK-thr306 acting as a Molecule in Ajay_Bhalla_2004_Feedback_Tuning Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | CaMK-thr306 | Ajay_Bhalla_
2004_Feedback_
Tuning
Accession No. : 78 | CaMKII
Pathway No. : 357 | 0 | 1.5 | No | | This forms due to basal autophosphorylation, but I think it has to be considered as a pathway even if some CaM is floating around. In either case it will tend to block further binding of CaM, and will not display any enzyme activity. See Hanson and Schulman JBC 267:24 pp17216-17224 1992 |
CaMK-thr306 acting as a Substrate for an Enzyme in Ajay_Bhalla_2004_Feedback_Tuning Network
CaMK-thr306 acting as a Product of an Enzyme in Ajay_Bhalla_2004_Feedback_Tuning Network
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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