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Molecule Parameter List for BDNF

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
BDNF participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1000010

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
BDNF_Receptor86Network
Shared_Object_BDNF_Receptor TrKB_mod PI3K_mod 
BDNF recetor signaling is one of the sub-model in BDNF signaling cascade. BDNF activates TrKB, leading to the stimulation of PI3K and formation of PIP3.

BDNF acting as a Molecule in  
BDNF_Receptor Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
BDNFBDNF_Receptor
Accession No. : 86
  • Shared_Object_
    BDNF_Receptor

    Pathway No. : 1082
  • 0.0001999.97Yes

    BDNF acting as a Substrate in a reaction in  
    BDNF_Receptor Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
    Ligand_bindingBDNF_Receptor
    Accession No. : 86
    TrKB_mod
    Pathway No. : 1083
    1.0001
    (uM^-1 s^-1)
    0.05
    (s^-1)
    Kd(bf) = 0.05(uM)-Substrate
    BDNF
    TrKB

    Product
    BDNF_TrkB_clx



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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