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Molecule Parameter List for PIP3_AKT_thr308

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

PIP3_AKT_thr308 participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	0	2	2	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
mTOR_pathway	92	Network	Shared_Object_mTOR_pathway,  AKT_mod,  S6Kinase,   PI3K_mod,  TrKB_mod,  mTOR_model,   MAPK,  PKC,  4E-BP_mod,   Ras,  Sos,  43S_complex,   CaM
This model consists of various sub-modules. They are as follows: 1) BDNF receptor signaling 2) AKT signaling 3) 4E-BP model 4) S6 Kinase model 5) CaMKIII model 6) Protein synthesis model 7) CaM 8) PKC 9) MAPK model.

PIP3_AKT_thr308 acting as a Molecule in  mTOR_pathway Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
PIP3_AKT_thr308	mTOR_pathway Accession No. : 92	AKT_mod Pathway No. : 1098	0	1000	No

PIP3_AKT_thr308 acting as a Substrate for an Enzyme in  mTOR_pathway Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PP2A  / Dephosph_ AKTthr308	mTOR_pathway Accession No. : 92	Shared_Object_ mTOR_pathway Pathway No. : 1097	4.80015	1.8	4	explicit E-S complex	Substrate PIP3_AKT_thr308 Product PIP3_AKT
2	PIP3_PDK2  / phosp_AKTser473	mTOR_pathway Accession No. : 92	AKT_mod Pathway No. : 1098	0.800013	20	4	explicit E-S complex	Substrate PIP3_AKT_thr308 Product PIP3_AKT-t308_ s473

PIP3_AKT_thr308 acting as a Product of an Enzyme in  mTOR_pathway Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	PP2A  / Dephos_ AKTser473	mTOR_pathway Accession No. : 92	Shared_Object_ mTOR_pathway Pathway No. : 1097	4.8	1.8	4	explicit E-S complex	Substrate PIP3_AKT-t308_ s473 Product PIP3_AKT_thr308
2	PIP3_PDK1  / phospho_thr308	mTOR_pathway Accession No. : 92	AKT_mod Pathway No. : 1098	0.399987	10	4	explicit E-S complex	Substrate PIP3_AKT Product PIP3_AKT_thr308