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Molecule Parameter List for BDNF_TrkB2_star_clx

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

BDNF_TrkB2_star_clx participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	2	0	0	1	1

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
mTOR_pathway	92	Network	Shared_Object_mTOR_pathway,  AKT_mod,  S6Kinase,   PI3K_mod,  TrKB_mod,  mTOR_model,   MAPK,  PKC,  4E-BP_mod,   Ras,  Sos,  43S_complex,   CaM
This model consists of various sub-modules. They are as follows: 1) BDNF receptor signaling 2) AKT signaling 3) 4E-BP model 4) S6 Kinase model 5) CaMKIII model 6) Protein synthesis model 7) CaM 8) PKC 9) MAPK model.

BDNF_TrkB2_star_clx acting as a Molecule in  mTOR_pathway Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
BDNF_TrkB2_star_clx	mTOR_pathway Accession No. : 92	TrKB_mod Pathway No. : 1101	0	1000	No

BDNF_TrkB2_star_clx acting as an Enzyme in  mTOR_pathway Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	BDNF_TrkB2_ star_clx / PLC_g_phospho	mTOR_pathway Accession No. : 92	TrKB_mod Pathway No. : 1101	0.300008	0.5	4	explicit E-S complex	Substrate PLC_g Product PLC_g_star
2	BDNF_TrkB2_ star_clx / Shc_phospho	mTOR_pathway Accession No. : 92	TrKB_mod Pathway No. : 1101	0.833306	0.3	4	explicit E-S complex	Substrate Shc Product Shc_star

BDNF_TrkB2_star_clx acting as a Substrate in a reaction in  mTOR_pathway Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
LR_Internalize	mTOR_pathway Accession No. : 92	TrKB_mod Pathway No. : 1101	0.01 (s^-1)	0 (uM^-1 s^-1)	-	-	Substrate BDNF_TrkB2_ star_clx Product Int_BDNF_TrKB2_ star_clx Int_BDNF_TrKB2_ star_clx

BDNF_TrkB2_star_clx acting as a Product in a reaction in  mTOR_pathway Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
Autophos_TrKB	mTOR_pathway Accession No. : 92	TrKB_mod Pathway No. : 1101	0.02 (s^-1)	0 (s^-1)	-	-	Substrate BDNF_TrkB2_clx Product BDNF_TrkB2_ star_clx