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Molecule Parameter List for 40S

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

40S participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	0	0	0	3	3	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
mTOR_pathway	92	Network	Shared_Object_mTOR_pathway,  AKT_mod,  S6Kinase,   PI3K_mod,  TrKB_mod,  mTOR_model,   MAPK,  PKC,  4E-BP_mod,   Ras,  Sos,  43S_complex,   CaM
This model consists of various sub-modules. They are as follows: 1) BDNF receptor signaling 2) AKT signaling 3) 4E-BP model 4) S6 Kinase model 5) CaMKIII model 6) Protein synthesis model 7) CaM 8) PKC 9) MAPK model.

40S acting as a Molecule in  mTOR_pathway Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
40S	mTOR_pathway Accession No. : 92	Shared_Object_ mTOR_pathway Pathway No. : 1097	0	1000	No
Activated form of S6

40S acting as a Product of an Enzyme in  mTOR_pathway Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	S6K_thr-412  / S6_phos	mTOR_pathway Accession No. : 92	S6Kinase Pathway No. : 1099	0.250003	0.01	4	explicit E-S complex	Substrate 40S_inact Product 40S
2	S6K_thr-252  / S6_phospho	mTOR_pathway Accession No. : 92	Shared_Object_ mTOR_pathway Pathway No. : 1097	0.250003	0.1	4	explicit E-S complex	Substrate 40S_inact Product 40S
3	40S_basal  / basal	mTOR_pathway Accession No. : 92	Shared_Object_ mTOR_pathway Pathway No. : 1097	0.250003	0.1	4	explicit E-S complex	Substrate 40S_inact Product 40S

40S acting as a Substrate in a reaction in  mTOR_pathway Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	S6_dephosph	mTOR_pathway Accession No. : 92	S6Kinase Pathway No. : 1099	0.01 (s^-1)	0 (s^-1)	-	-	Substrate 40S Product 40S_inact
2	Q_binds_R	mTOR_pathway Accession No. : 92	43S_complex Pathway No. : 1108	0.48 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 1.0417(uM)	-	Substrate 40S Quaternary_clx Product Q.R
3	R_binds_M	mTOR_pathway Accession No. : 92	43S_complex Pathway No. : 1108	1.28 (uM^-1 s^-1)	0.719 (s^-1)	Kd(bf) = 0.5617(uM)	-	Substrate 40S eIF4F-mRNA_clx Product RM