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Molecule Parameter List for PKC-DAG-memb_star | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| PKC-DAG-memb_star participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 1 | 0 | 0 | 0 | 0 | 1 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| mTOR_pathway | 92 | Network | Shared_Object_mTOR_pathway, AKT_mod, S6Kinase, PI3K_mod, TrKB_mod, mTOR_model, MAPK, PKC, 4E-BP_mod, Ras, Sos, 43S_complex, CaM |
| This model consists of various sub-modules. They are as follows: 1) BDNF receptor signaling 2) AKT signaling 3) 4E-BP model 4) S6 Kinase model 5) CaMKIII model 6) Protein synthesis model 7) CaM 8) PKC 9) MAPK model. | |||
PKC-DAG-memb_star acting as a Molecule in mTOR_pathway Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered |
| PKC-DAG-memb_star | mTOR_pathway Accession No. : 92 | PKC Pathway No. : 1104 | 0 | 1000 | No |
PKC-DAG-memb_star acting as a Summed Molecule in mTOR_pathway Network
| Accession Name | Pathway Name | Target | Input |
| mTOR_pathway Accession No. : 92 | mTOR_pathway Pathway No. : 1097 | PKC-active | PKC-DAG-AA_star star PKC-Ca-AA_star star PKC-basal_star PKC-AA_star |
| Conc of PKC in brain is about 1 uM (?) | |||
PKC-DAG-memb_star acting as a Product in a reaction in mTOR_pathway Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents |
| PKC-DAG-to-memb | mTOR_pathway Accession No. : 92 | PKC Pathway No. : 1104 | 1 (s^-1) | 0.1 (s^-1) | Keq = 0.1(uM) | 0.909sec | Substrate PKC-Ca-DAG Product star |
| Raise kb from .087 to 0.1 to match data from Shinomura et al. Lower kf from 1.155 to 1.0 to match data from Shinomura et al. | |||||||