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Molecule Parameter List for Ras-GTP_PI3K

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
Ras-GTP_PI3K participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences1010001

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
mTOR_pathway92Network
Shared_Object_mTOR_pathway AKT_mod S6Kinase 
PI3K_mod TrKB_mod mTOR_model 
MAPK PKC 4E-BP_mod 
Ras Sos 43S_complex 
CaM 
This model consists of various sub-modules. They are as follows: 1) BDNF receptor signaling 2) AKT signaling 3) 4E-BP model 4) S6 Kinase model 5) CaMKIII model 6) Protein synthesis model 7) CaM 8) PKC 9) MAPK model.

Ras-GTP_PI3K acting as a Molecule in  
mTOR_pathway Network
NameAccession NamePathway NameInitial Conc.
(uM)
Volume
(fL)
Buffered
Ras-GTP_PI3KmTOR_pathway
Accession No. : 92
  • Shared_Object_
    mTOR_pathway

    Pathway No. : 1097
  • 01000No

    Ras-GTP_PI3K acting as an Enzyme in  
    mTOR_pathway Network
    Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    Ras-GTP_PI3K /
  • PIP2_phospho_
    Ras-GTP
  • mTOR_pathway
    Accession No. : 92
  • Shared_Object_
    mTOR_pathway

    Pathway No. : 1097
  • 4.0000244explicit E-S complexSubstrate
    PIP2

    Product
    PIP3

    Ras-GTP_PI3K acting as a Product in a reaction in  
    mTOR_pathway Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
    NameAccession NamePathway NameKfKbKdtauReagents
  • PI3K_bind_
    Ras-GTP
  • mTOR_pathway
    Accession No. : 92
  • Shared_Object_
    mTOR_pathway

    Pathway No. : 1097
  • 1.7999
    (uM^-1 s^-1)
    5
    (s^-1)
    Kd(bf) = 2.7779(uM)-Substrate
    GTP-Ras
    PI3K

    Product
    Ras-GTP_PI3K