| |
Name | Accession
Type | Initial
Conc.
(uM) | Volume
(fL) | Buffered | Sum Total Of |
| 1 | AC1-CaM | Network | 0 | 0 | No | - |
| | This version of cyclase is Calmodulin activated. Gs stims it but betagamma inhibits. |
| 2 | AC1 | Network | 0.02 | 0 | No | - |
| | Starting conc at 20 nM. |
| 3 | AC2* | Network | 0 | 0 | No | - |
| | This version is activated by Gs and by a betagamma and phosphorylation. |
| 4 | AC2-Gs | Network | 0 | 0 | No | - |
| 5 | AC2 | Network | 0.015 | 0 | No | - |
| | Starting at 0.015 uM. |
| 6 | AC1-Gs | Network | 0 | 0 | No | - |
| 7 | AMP | Network | 325490 | 0 | No | - |
| 8 | AC2*-Gs | Network | 0 | 0 | No | - |
| 9 | cAMP-PDE | Network | 0.45 | 0 | No | - |
| | The levels of the PDE are not known at this time. However, enough kinetic info and info about steady-state levels of cAMP etc are around to make it possible to estimate this. |
| 10 | cAMP-PDE* | Network | 0 | 0 | No | - |
| | This form has about 2X activity as plain PDE. See Sette et al JBC 269:28 18271-18274 1994. |
| 11 | PDE1 | Network | 2 | 0 | No | - |
| | CaM-Dependent PDE. Amount calculated from total rate in brain vs. specific rate. |
| 12 | CaM.PDE1 | Network | 0 | 0 | No | - |
| | Activity up 6x following Ca-CaM binding. |
| 13 | ATP | Network | 5000 | 0 | Yes | - |
| | ATP is present in all cells between 2 and 10 mM. See Lehninger. |
and 
color.