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Enzyme List for pathway condorelliGCmod (Pathway Number 89)

 Molecule Name/
Site Name
Km (uM) kcat (1/s)Ratio
(k2/k3)
Enzyme TypeSubstrate Product
1 Enzyme Activity:
full_act_sGC

Enzyme Molecule:
NO_sGCfull_act
57.9996404explicit E-S complexGTP
cGMP
  Km values for the basal and fully activated forms of sGC have been determined as 85-120 uM and 58 uM, respectively ... (Ignarro et al., 1982, BBA, 718:49-59)..and the same has been used by Condorelli et al., 2001... Vmax values are around 10-100 nmol/min/mg (without NO) and 10-40 umol/min/mg (with NO) ..... thru personal correspondence with T Bellamy, UK.

Pathway DetailMolecule ListEnzyme ListReaction List