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Accession Type:
Network
MAPK_network_
2003
Shared_Object_
MAPK_network_
2003
PKC
PLA2
PLCbeta
Gq
MAPK
Ras
EGFR
Sos
PLC_g
CaMKII
CaM
PP1
PP2B
PKA
AC
 Molecule
 Enzyme
 Reaction

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Molecule List for pathway AC (Pathway Number 221)

 Name Initial Conc. (uM) Volume (fL) Buffered
1AC10.021000No
    Starting conc at 20 nM.
2AC1-CaM01000No
    This version of cyclase is Calmodulin activated. Gs stims it but betagamma inhibits.
3AC1-Gs01000No
   
4AC20.0151000No
    Starting at 0.015 uM.
5AC2*01000No
    This version is activated by Gs and by a betagamma and phosphorylation.
6AC2*-Gs01000No
   
7AC2-Gs01000No
   
8AMP3254900.0016667No
   
9ATP50001000Yes
    ATP is present in all cells between 2 and 10 mM. See Lehninger.
10CaM.PDE101000No
    Activity up 6x following Ca-CaM binding.
11cAMP-PDE0.451000No
    The levels of the PDE are not known at this time. However, enough kinetic info and info about steady-state levels of cAMP etc are around to make it possible to estimate this.
12cAMP-PDE*01000No
    This form has about 2X activity as plain PDE. See Sette et al JBC 269:28 18271-18274 1994.
13PDE121000No
    CaM-Dependent PDE. Amount calculated from total rate in brain vs. specific rate.


Pathway Details  Molecule List   Enzyme List   Reaction List  


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