| Name | Initial Conc. (uM) td> | Volume (fL) | Buffered |
1 | AC1 | 0.02 | 1000 | No |
| Starting conc at 20 nM. |
2 | AC1-CaM | 0 | 1000 | No |
| This version of cyclase is Calmodulin activated. Gs stims it but betagamma inhibits. |
3 | AC1-Gs | 0 | 1000 | No |
| |
4 | AC2 | 0.015 | 1000 | No |
| Starting at 0.015 uM. |
5 | AC2* | 0 | 1000 | No |
| This version is activated by Gs and by a betagamma and phosphorylation. |
6 | AC2*-Gs | 0 | 1000 | No |
| |
7 | AC2-Gs | 0 | 1000 | No |
| |
8 | AMP | 325490 | 0.0016667 | No |
| |
9 | ATP | 5000 | 1000 | Yes |
| ATP is present in all cells between 2 and 10 mM. See Lehninger. |
10 | CaM.PDE1 | 0 | 1000 | No |
| Activity up 6x following Ca-CaM binding. |
11 | cAMP-PDE | 0.45 | 1000 | No |
| The levels of the PDE are not known at this time. However, enough kinetic info and info about steady-state levels of cAMP etc are around to make it possible to estimate this. |
12 | cAMP-PDE* | 0 | 1000 | No |
| This form has about 2X activity as plain PDE. See Sette et al JBC 269:28 18271-18274 1994. |
13 | PDE1 | 2 | 1000 | No |
| CaM-Dependent PDE. Amount calculated from total rate in brain vs. specific rate. |