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Accession Type:
Network
RanGTPase
Shared_Object_
RanGTPase
Nucleus
 Molecule
 Reaction
Cytoplasm

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Molecule List for pathway Nucleus (Pathway Number 305)

 Name Initial Conc. (uM) Volume (fL) Buffered
1GDP012000No
    GDP released from RCC1-GDP.Ran complex Nuclear Volume = 1.2 pL = 1.2e-15 m^3 Footnote for Table 2 Gorlich D et al (2003) EMBO J 22(5):1088-1100
2GDP.Ran-nuclear012000No
    nuclear-GDP.Ran Nuclear fraction of GDP bound Ran Approximately 71% of RanGDP in the nucleus is bound Nuclear volume = 1.2 pL = 1.2e-15 m^3 Gorlich D et al (2003) EMBO J 22(5):1088-1100
3GTP500.00712000No
    GTP Initial GTP concentration = 500uM Nuclear volume = 1.2 pL = 1.2e-15 m^3 Table II footnote Gorlich D et al (2003) EMBO J 22(5):1088-1100
4GTP.Ran-nuclear012000No
    nuclear-GTP.Ran Nuclear fraction of Ran-GTP complex Nuclear volume = 1.2 pL = 1.2e-15 m^3 Footnote for Table 2 Gorlich D et al (2003) EMBO J 22(5):1088-1100
5nuclear-NTF2-GDP.Ran012000No
    NTF2-GDP.Ran Cytoplasmic fraction of GDP bound Ran complexed with NTF2 Nuclear volume = 1.2 pL = 1.2e-15 m^3 Footnote for Table 2 Gorlich D et al (2003) EMBO J 22(5):1088-1100 Initial cytoplasmic GDP.Ran concentration = 5 uM Table II footnote
6RCC10.712000No
    RCC1 Nuclear volume = 1.2 pL = 1.2e-15 m^3 Nuclear concentration of RCC1 = 0.7 uM Supplementary Table B Gorlich D et al (2003) EMBO J 2003, 22(5):1088-1100
7RCC1-GDP.Ran012000No
    RCC1-GDP.Ran Ran-GDP complex bound to RCC1 Catherine Chaillan-Huntington et al (2000) J.Biol.Chem. 275(8):5874-5879. Nuclear volume = 1.2pL = 1.2e-15 m^3 Gorlich D et al (2003) EMBO J 22(5):1088-1100
8RCC1-Ran012000No
    RCC1-GDP.Ran Ran-GDP complex bound to RCC1 Nuclear volume = 1.2pL = 1.2e-15 m^3 Footnote for Table 2 Gorlich D et al (2003) EMBO J 22(5):1088-1100
9RCC1-RanGTP012000No
    RCC1-GTP.Ran Ran-GTP complex bound to RCC1 Nuclear volume = 1.2 pL = 1.2e-15 m^3 Footnote for Table 2 Gorlich D et al (2003) EMBO J 22(5):1088-1100


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