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Accession Type:
Network
4EBP
Shared_Object_
4EBP
 Molecule
 Enzyme
 Reaction
mTOR_model
4E-BP_mod

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Reaction List for pathway Shared_Object_4EBP (Pathway Number 1090)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 eIF4E-BP_disso1
(s^-1)
0.1
(uM^-1 s^-1)
Kd(cb) = 0.1(uM)-
  • eIF4E-BP_thr37_
    46

  • 4E-BP_t37_46
    eIF4E
    2 eIF4F_clx30.0001
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.0033(uM)-eIF4G-A_clx
    eIF4E
    eIF4F
    3 eIF4F_mRNA_clx0.2
    (uM^-1 s^-1)
    0.077
    (s^-1)
    Kd(bf) = 0.385(uM)-mRNA
    eIF4F
    eIF4F-mRNA_clx
    4 eIF4G_A_clx0.3
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 3.3333(uM)-eIF4A
    eIF4G
    eIF4G-A_clx


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    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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