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Molecule Parameter List for eIF4F | The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by  color. | | Statistics |
Accession and Pathway Details | |
| Accession Name | Accession No. | Accession Type | Pathway Link | | 4EBP | 89 | Network |
Shared_Object_4EBP, mTOR_model, 4E-BP_mod | | Rheb-GTP activates mTOR, again with regulation by MAPK, leading to formation of the eIF4F-mRNA complex. |
eIF4F acting as a Molecule in 4EBP Network
| Name | Accession Name | Pathway Name | Initial Conc.
(uM) | Volume
(fL) | Buffered | | eIF4F | 4EBP
Accession No. : 89 | Shared_Object_
4EBP
Pathway No. : 1090 | 0 | 1000 | No |
eIF4F acting as a Substrate in a reaction in 4EBP Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | eIF4F_mRNA_clx | 4EBP
Accession No. : 89 | Shared_Object_
4EBP
Pathway No. : 1090 | 0.2
(uM^-1 s^-1) | 0.077
(s^-1) | Kd(bf) = 0.385(uM) | - | Substrate
eIF4F
mRNA
Product
eIF4F-mRNA_clx
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eIF4F acting as a Product in a reaction in 4EBP Network
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated.
Kd for higher order reaction are not consider. |
| Name | Accession Name | Pathway Name | Kf | Kb | Kd | tau | Reagents | | eIF4F_clx | 4EBP
Accession No. : 89 | Shared_Object_
4EBP
Pathway No. : 1090 | 30.0001
(uM^-1 s^-1) | 0.1
(s^-1) | Kd(bf) = 0.0033(uM) | - | Substrate
eIF4E
eIF4G-A_clx
Product
eIF4F
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| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
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