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Reaction List for pathway PI3K_mod (Pathway Number 1100) |
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
| Name | Kf | Kb | Kd | tau | Substrate | Product | |
| 1 | basal_PI3K_act | 0.0007 (s^-1) | 0.45 (s^-1) | Keq = 661.7647(uM) | 2.219sec | PI3K | PI3K_basal |
| 2 | bind_Gab1 | 0.3 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 3.3333(uM) | - | Gab1 clx | Grb2-Gab1_clx |
| 3 | Grb2_bind_Shc | 1 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 1(uM) | - | Grb2 Shc_star | clx |
| 4 | PI3K_act | 5.0002 (uM^-1 s^-1) | 0.08 (s^-1) | Kd(bf) = 0.016(uM) | - | PI3K Grb2-Gab1_clx | Grb2-Gab1_PI3K_ clx |
| 5 | Shc_star_ dephospho | 0.2 (s^-1) | 0 (s^-1) | - | - | Shc_star | Shc |
| Pathway Detail | Molecule List | Enzyme List | Reaction List |