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Reaction List for pathway TrKB_mod (Pathway Number 1101)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 Autophos_TrKB0.02
(s^-1)
0
(s^-1)
--BDNF_TrkB2_clx
  • BDNF_TrkB2_
    star_clx

  • 2 Dimeriz_TrKB1
    (uM^-1 s^-1)
    0.02
    (s^-1)
    Kd(bf) = 0.02(uM)-BDNF_TrkB_clx
    TrKB
    BDNF_TrkB2_clx
    3 Ligand_binding1.0001
    (uM^-1 s^-1)
    0.05
    (s^-1)
    Kd(bf) = 0.05(uM)-TrKB
    BDNF
    BDNF_TrkB_clx
    4 LR_cycling0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500sec
  • Int_BDNF_TrKB2_
    star_clx

  • TrKB
    5 LR_Internalize0.01
    (s^-1)
    0
    (uM^-1 s^-1)
    --
  • BDNF_TrkB2_
    star_clx

  • Int_BDNF_TrKB2_
    star_clx

  • Int_BDNF_TrKB2_
    star_clx

  • 6 PLC_g_star_
    dephospho
    0.07
    (s^-1)
    0
    (s^-1)
    --PLC_g_star
    PLC_g

    Pathway DetailMolecule ListEnzyme ListReaction List