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Reaction List for pathway MAPK (Pathway Number 139) |
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
|   | Name | Kf | Kb | Kd | tau | Substrate | Product |
| 1 | Neg_feedback | 1 (uM^-1 s^-1) | 0.009 (s^-1) | Kd(bf) = 0.009(uM) | - | MAPK-PP Ras-MKKKK | |
| From Kholodenko, 2000 Eur J Biochem 267 the Kd is 9 nM. We use a rather fast Kf of 1/sec/uM so that equilibrium is maintained. | |||||||
| Pathway Detail | Molecule List | Enzyme List | Reaction List |