NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Accession Type:
Network
Ajay_Bhalla_
2004_Feedback_
Tuning
Shared_Object_
Ajay_Bhalla_
2004_Feedback_
Tuning
PKC
PLA2
PLCbeta
Gq
MAPK
Ras
EGFR
Sos
PLC_g
CaMKII
CaM
PP1
 Molecule
 Reaction
PP2B
PKA
AC

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Reaction List for pathway PP1 (Pathway Number 359)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 dissoc-PP1-I11
(s^-1)
0
(uM^-1 s^-1)
--PP1-I1
PP1-active
I1
  Let us assume that the equil in this case is very far over to the right. This is probably safe.
2 Inact-PP1499.977
(uM^-1 s^-1)
0.1
(s^-1)
Kd(bf) = 0.0002(uM)-I1*
PP1-active
PP1-I1*
  K inhib = 1nM from Cohen Ann Rev Bioch 1989, 4 nM from Foukes et al Assume 2 nM. kf /kb = 8.333e-4


Pathway Details   Molecule List  Enzyme List  Reaction List  


Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.