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Parameters for NOS (Pathway Number 90)

Pathway Layout

Pathway Basic Parameters

Pathway NameNOS
Pathway Entry Number 90
Accession Number 20
Accession Name NOS_Phosph_regulation
Species rat; Mammalian
Tissue Brain - Neuronal; expressed in E.coli
CellCompartmentCytosol
Related Pathways 65, 66
Notes This model features the phosphorylation of rat brain neuronal NOS expressed in E. coli or Sf9 cells, which leads to a decrease in Vmax of the phosphorylated enzyme, with little change of both the Km for L-arginine and Kact for CaM. This is based on Hayashi Y. et al. J Biol Chem. (1999) 274(29):20597-602. They report of phosphorylatin being carried out by CaM kinases I alpha, II alpha and IV. The rates used have been obtained from their paper and from other reported experimental data.

Statistics

10
4
2

Conversion format

This pathway is part of accession 20 and is completely specified in the file acc20.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc20.g   
GENESIS Format (Annotated version)    Anno_acc20.g   
SBML format    acc20.xml   
Pathway DetailMolecule ListEnzyme ListReaction List