|
Enter a Search String | | Special character and space not allowed in the query term.
Search string should be at least 2 characters long. |
Molecule List for pathway NOS (Pathway Number 90) | | Name | Initial Conc. (uM) | Volume (fL) | Buffered | | 1 | Ca-CaMnNOS | 0 | 0.0016667 | No | | | | | 2 | CaM-Ca4 | 20 | 0.0016667 | Yes | | | | | 3 | CaMKIalpha | 1 | 0.0016667 | Yes | | | Phosphorylates nNOS, but not as effective as CaMKIIalpha. (Hayashi et al., 1999,JBC,274(29):20597-20602.) Report of Plateau Level in their phosphorylation plots reaching after 100 min. -- ~0.4 mol of 32p/mol of nNOS. | | 4 | CaMKIIalpha | 1 | 0.0016667 | Yes | | | CaMKIIalpha caused the most rapid phosphorylation of nNOS, with half-maximal phosphorylation apparent at 3 min and plateau level at 10 min. (Hayashi et al., 1999,JBC,274(29):20597-20602). The Maximal Phosphorylation of nNOS was observed at ~0.4 mol of 32p/mol of nNOS under their expt conditions. | | 5 | CaMKIV | 1 | 0.0016667 | Yes | | | Activity is similar to CaMKIalpha, with ~0.7 mol of 32p/mol of nNOS. (Hayashi et al., 1999,JBC,274(29):20597-20602) | | 6 | cit | 0 | 0.0016667 | No | | | | | 7 | Larg | 100 | 0.0016667 | No | | | | | 8 | nNOS | 0.5 | 0.0016667 | No | | | neuronal Nitric Oxide Synthase. Found in the neurons, activity is dependent on CaM binding, in response to Ca levels. Molecular weight ~160 kDa. This is unphosporylated form of nNOS. | | 9 | NO | 0 | 0.0016667 | No | | | | | 10 | NOS* | 0 | 0.0016667 | No | | | Phosporylated NOS, by CaM kinases, with lowering of Vmax, but little change in Km for Arg and Kact for CaM. (Hayashi et al., JBC, 1999, 274(29):20597-20602) |
Pathway Details Molecule List Enzyme List Reaction List
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details. |
|
