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Accession Type:
Pathway
CDK2-CyclinA_
activation_
improved
CDK2_CyclinA_
activation_
improved

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Accession information for CDK2-CyclinA_activation_improved (Accession Number 43)

Reaction Scheme

Accession Basic Parameters

Name CDK2-CyclinA_activation_improved
Accession Type Pathway
Transcriber Sharat J. Vayttaden, NCBS
Developer May C. Morris, Claire Gondeau, John A. Tainer and Gilles Divita
Entry Date (YYYY-MM-DD) 2003-01-11
Species Human, Xenopus
Tissue Expressed in E.coli
Cell Compartment Cytosol
Source Morris MC. et al. J Biol Chem. (2002) 277(26):23847-53. ( peer-reviewed publication )
Methodology Quantitative match to experiments
Model Implementation Exact GENESIS implementation
Model Validation Approximates original data
Notes This version of the model for CDK2/Cyclin A complex activation (expressed in E. coli) is a good match to the data and the simulation matches the graphs Fig.1B and Fig.1B inset. The rate constants though differ from the rate constants in Morris MC. et al. J Biol Chem. (2002) 277(26):23847-53.

Conversion formats

FormatFile
Native Format (GENESIS format)    acc43.g   
GENESIS Format (Annotated version)    Anno_acc43.g   
MATLAB format    acc43.m   
SBML format    acc43.xml   



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